RADICALS is a large clinical trial which is taking place in the UK, Canada, Denmark and the Republic of Ireland at the moment.
It is a phase III randomised controlled trial that will recruit approximately 3000 men to help answer two important questions for men who have had surgery for prostate cancer:
In breast cancer, surgery is followed by radiotherapy and hormone treatment, because the combination is better than surgery alone. In prostate cancer, surgery alone is a standard treatment, and we are not sure how best to use radiotherapy and hormone treatment after surgery.
The trial may be suitable at some point for most men who have a radical prostatectomy.
We are delighted to inform you that RADICALS closed to recruitment on 30th December 2016. The trial randomised 2840 patients to RADICALS-HD and 1396 patients to RADICALS-RT. This is a huge achievement and we would like to say thank you to all the patients who participated in the trial and the trial teams at our recruiting centres.