About RADICALS
RADICALS is a large clinical trial which is taking place
in the UK and Canada at the
moment.
It is a phase III randomised controlled trial that will recruit
4000 men to help answer two important questions for men who have
had surgery for prostate cancer:
- Which is the best way to use radiotherapy after surgery?
- Which is the best way to use hormone treatment with any
radiotherapy given after surgery
In breast cancer, surgery is followed by radiotherapy and
hormone treatment, because the combination is better than surgery
alone. In prostate cancer, surgery alone is a standard
treatment, and we are not sure how best to use radiotherapy and
hormone treatment after surgery.
The trial may be suitable at some point for most men who have a
radical prostatectomy.
Read more about RADICALS
News
1st February 2010
There has been an important change to the RADICALS trial which
makes recruitment to the trial much simpler for patients and
clinicians.
RADICALS is an international, multi-centre, randomised
controlled trial for men with prostate cancer. It has two
randomisations for overlapping patient groups: the Radiotherapy
(RT) Timing Randomisation and the Hormone Duration Randomisation.
Accrual to these comparisons has now been completely separated.
Read more