- About RADICALS
- Information for Patients
- Information for participating and interested centres
- CCTG website for Canadian participants
- MRC CTU Contacts
- Useful links
RADICALS is a large clinical trial which is taking place in the UK, Canada, Denmark and the Republic of Ireland at the moment. It is a phase III randomised controlled trial that will recruit approximately 3000 men to help answer two important questions for men who have had surgery for prostate cancer:
In breast cancer, surgery is followed by radiotherapy and hormone treatment, because the combination is better than surgery alone. In prostate cancer, surgery alone is a standard treatment, and we are not sure how best to use radiotherapy and hormone treatment after surgery.
The trial may be suitable at some point for most men who have a radical prostatectomy.
RADICALS may be suitable both for:
Men who need radiotherapy after their operation can enter into the Hormone Duration Comparison of RADICALS.
Men for whom there is uncertainty about whether radiotherapy is needed straight after the operation can join the Radiotherapy Timing Comparison. If they wish to, they can also join the Hormone Duration Comparison.