About RADICALS     

RADICALS is a large clinical trial which is taking place in the UK, Canada, Denmark and the Republic of Ireland at the moment.

It is a phase III randomised controlled trial that will recruit approximately 3000 men to help answer two important questions for men who have had surgery for prostate cancer:

  • Which is the best way to use radiotherapy after surgery?
  • Which is the best way to use hormone treatment with any radiotherapy given after surgery 

In breast cancer, surgery is followed by radiotherapy and hormone treatment, because the combination is better than surgery alone.  In prostate cancer, surgery alone is a standard treatment, and we are not sure how best to use radiotherapy and hormone treatment after surgery.

The trial may be suitable at some point for most men who have a radical prostatectomy.

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News

2nd December 2011

Updated CRFs have been sent to all centres and can also be found on the Information for participating centres page here. Please ensure you are using the correct version each CRF.  

24th November 2011

The latest editions of the RADICALS newsletters are available to read here:

RADICALS-RT Newsletter                 RADICALS-HD Newsletter

23rd November 2011

The Quality of Life assessment is one of the most important assessments in RADICALS-RT as there is currently limited patient-reported data on symptoms and morbidities associated with treatments after radical prostatectomy. All RADICALS-RT patients are encouraged to contribute to this part of RADICALS.

It is important that centre staff remember to ask these patients to complete the forms at baseline, year one, year five and year ten. Centres will be receiving information soon regarding their quality of life compliance rates.

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Latest Updates

Accrual

31/12/11
Latest Accrual figures

News

02/12/11
Latest versions of RADICALS CRFs for participating centres available online now

Videos

01/10/10
YouTube Video: Hormone Duration Randomisation - Q&A Section Part 1


More videos