RADICALS is a large clinical trial which is taking place in the UK, Canada, Denmark and the Republic of Ireland.

It is a phase III randomised controlled trial that recruited nearly 4000 men from 149 centres over 9 years. This makes it the largest trial to be conducted on this population group. RADICALS will help to answer two important questions for men who have had surgery for prostate cancer:

  • Which is the best way to use radiotherapy after surgery?
  • Which is the best way to use hormone treatment with any radiotherapy given after surgery?

In breast cancer, surgery is followed by radiotherapy and hormone treatment, because the combination is better than surgery alone. In prostate cancer, surgery alone is a standard treatment, and we are not sure how best to use radiotherapy and hormone treatment after surgery.

 

Latest News

NCRI Prostate Cancer Group has cited RADICALS-RT as one of their top 3 achievements of the year

We are delighted to share with you that The National Cancer Research Institute (NCRI) Prostate Cancer Group has cited RADICALS-RT as one of their top 3 achievements of the year in their 2019-2020 annual report! Read more...

Randomisation

How to enter patients

Accrual

Recruitment rates to date

CCTG

Website for Canadian participants